Human umbilical cord blood stem cell culture supernatant
The Source of Timeless Beauty
“sen” Transform your skin’s future at the cellular level.
Highly purified exosomes penetrate deep into your skin.
Made in Japan
The Mechanism of Skin Aging
As we age, the skin’s natural renewal process, known as turnover, gradually slows down.
This causes dead skin cells to accumulate on the surface, leading to a rough texture and dull appearance.
Additionally, the body’s production of collagen and elastin decreases, resulting in the formation of wrinkles, sagging, and loss of elasticity.
Nutrient and moisture delivery throughout the skin becomes compromised, and the skin’s natural barrier weakens, making it more prone to dryness and irritation.
“sen” works by addressing these root causes of skin aging, helping to reset and restore the natural skin cycle for healthier, more youthful skin.
Supports cellular repair and renewal
The skin’s natural regenerative power is something that daily skincare alone cannot fully support.
Stem cell beauty serums penetrate deep into the skin, helping to normalize cell turnover and support cellular repair.
“sen” is enriched with a high concentration of stem cell-derived exosomes,
providing fundamental care that traditional cosmetics simply cannot achieve.
Exosomes
The skin’s regenerative power is a miracle we are born with.
“sen” is luxuriously infused with exosomes extracted from human umbilical cord blood stem cell culture supernatant,
delivering targeted action deep into the skin to revive dry, dull, and sagging skin from within.
Additionally, its all-in-one formula condenses the steps of toner, serum, and cream into a single product,
bringing effortless luxury and innovation to your daily skincare routine.
Give your skin the ultimate gift of renewal.
Experience a new dimension of skincare with “sen” today.
Nurturing Care
Lotions and creams provide “protective care”,
while stem cell serums offer “nurturing care”.
By working directly on skin cells, they help restore firmness, radiance, and deep hydration from within.
“sen” stands at the forefront of this innovative new generation of skincare.
The Decline of Skin’s Regenerative Ability with Age
The exosomes in “sen” reinvigorate fatigued skin cells and reset the accumulation of damage,
making it a breakthrough solution in next-generation anti-aging skincare.
Exosomes act as natural messenger particles between cells, delivering signals to promote skin repair and regeneration.
They stimulate the production of collagen and elastin, helping to reduce the appearance of wrinkles, sagging, and enlarged pores,
ultimately restoring firmness and youthful radiance to the skin.
The Future of Skincare: From Protection to Nurturing
“sen” harnesses the most advanced innovations in stem cell research to deliver the miracle of skin regeneration.
Defy the effects of time and achieve skin that radiates with eternal beauty and brilliance.
The Promise of Youthful Skin Age
The younger your skin’s biological age, the more noticeably it radiates with firmness, glow, and clarity,
as well as enhanced makeup application and superior moisture retention.
“sen” helps support skin rejuvenation, delivering visible improvements that make you look forward to checking the mirror each day.
Youthful skin naturally has a stronger self-repair capacity and is more resistant to external damage such as UV rays and dryness.
With “sen’s” exosome-rich serum, restore your skin’s innate youthful qualities and experience timeless radiance that defies age.
Beauty Has No Age Limit
“sen” activates your skin cells’ natural regenerative power,
restoring youthfulness and confidence from within.
Open the door to a new skincare ritual today.
The Power of Stem Cells
Each organ in the human body contains stem cells.
As we age, these cells lose their function, which can lead to disease.
However, research in regenerative medicine has advanced significantly,
enabling damaged organs to be repaired and regenerated by transplanting human stem cells.
More recently, it has been discovered that applying cosmetics containing active substances secreted by human stem cells directly to the skin can activate skin cells and dramatically improve skin condition.
This goes beyond merely supplying ingredients; it is about reactivating the skin’s own natural processes.
By incorporating stem cell culture supernatant cosmetics into your routine,
you can rejuvenate your skin from within.
Self-Renewal
Stem cells have the ability to replicate themselves indefinitely, continuously generating new cells to replace old or damaged ones.
Multipotency
Stem cells can differentiate into various cell types, including skin cells, nerve cells, and muscle cells. This versatility plays a vital role in medical and aesthetic applications.
Repair Capability
Stem cells have the unique ability to repair damaged tissues and cells, helping to maintain youthful and healthy skin.
Signal Transmission
Stem cells send signals to surrounding cells, regulating their behavior to efficiently promote regeneration and repair.
Environmental Responsiveness
Stem cells can adapt to changes in the body’s environment, differentiating into necessary cell types and initiating repair processes as needed. This responsiveness makes them highly valuable for a wide range of applications.
Anti-Inflammatory Properties
Stem cells possess anti-inflammatory properties, helping to calm inflammation that can trigger many common skin problems, thereby promoting healthy, balanced skin.
Human Umbilical Cord Blood Stem Cell Culture Supernatant
The Remarkable Power of Human Umbilical Cord Blood Stem Cell Culture Supernatant
Celebrated as a “miracle liquid” in the fields of beauty and regenerative medicine,
human umbilical cord blood stem cell culture supernatant contains high concentrations of exosomes secreted by stem cells, which maximize the skin’s regenerative potential.
Exosomes deliver instructions to skin cells for repair and renewal, powerfully supporting the production of collagen and elastin.
This rare supernatant also contains growth factors, cytokines, amino acids, and other vital nutrients that promote skin rejuvenation.
It is a next-generation skincare ingredient renowned for providing firmness, elasticity, and radiance to aging skin.
Why Top Aesthetic Salons Use It
Leading aesthetic salons choose only the most advanced regenerative beauty ingredients for the final step of their treatments.
The combination of umbilical cord blood stem cell supernatant and high-concentration exosomes is perfect for delicate post-treatment skin.
It accelerates cellular repair and regeneration, delivering instant and long-lasting effects of clarity, firmness, and hydration.
“sen” has earned its reputation as the ultimate finishing touch trusted by professionals.
Comparison with Other Stem Cell-Derived Products
Pig-Derived Stem Cells
■Primarily used in cost-focused products
■Limited absorption and affinity with human skin, resulting in reduced effectiveness
Human Adipose-Derived Stem Cells
■Widely available due to lower cost
■Derived from fat cells, which offer lower regenerative and repair potential compared to umbilical cord blood
Human Umbilical Cord Blood Stem Cell Culture Supernatant
■Derived from ethically collected umbilical cord blood stem cells from babies at 40 weeks gestation
■Contains exceptionally high levels of growth factors, cytokines, and exosomes
■Maximizes the skin’s cellular repair and regenerative capabilities
■Used as a premium ingredient in medical beauty and high-end aesthetic salons
■“sen” exclusively uses this superior human umbilical cord blood stem cell culture supernatant
Difference from Powdered Stem Cell Products
Recently, powdered versions of stem cell culture supernatant have emerged in high-end markets.
However, heat and drying during the powdering process may degrade the active components and reduce their effectiveness.
“sen” maintains the supernatant in a fresh liquid state, ensuring rapid absorption and maximum performance from the moment it touches your skin.
“sen” offers uncompromising quality, safety, and results.
Among stem cell skincare products, it remains the premium choice for customers who demand proven luxury and efficacy.
The Secret of “sen” All-in-One Beauty Serum
All-in-One Beauty Serum
“sen” is an all-in-one beauty serum that simplifies your skincare routine.
Just one application before bed, after cleansing, combines the effects of toner, serum, and moisturizer.
Even those who have struggled to maintain a skincare routine can enjoy powerful skin regeneration in just 30 seconds a day with “sen.”
The Youngest Ethical Stem Cells Available
The stem cells used in “sen” are cultivated from the youngest ethically sourced umbilical cord cells available,
chosen for their exceptional immune regulation, repair, and rejuvenation abilities to create the ultimate skincare experience.
Scientifically Proven to Increase Collagen I & III
The stem cells used in “sen” have been scientifically shown to increase skin levels of collagen types I & III,
leading to greater elasticity, firmness, and a visible reduction of wrinkles and sagging.
Superior to Fat or Bone Marrow-Derived Stem Cells
Human umbilical cord blood stem cell culture supernatant promotes skin cell proliferation, reduces inflammation,
stimulates skin tissue regeneration, and enhances the synthesis of structural skin proteins that support healthy skin.
Skin Rejuvenation, Anti-Aging, and Firmness
Over 89 types of bioactive proteins work to repair, rejuvenate, and firm the skin.
Contains the Youth Protein GDF11
Recognized by Harvard researchers and published in leading academic journals,
GDF11, known as the “reversal aging gene”, enhances fibroblast activity, promoting collagen and elastin production for youthful skin regeneration and firmness.
Exosomes for Deep Skin Penetration
“sen” contains powerful exosomes that travel at incredible speed through skin layers,
delivering large amounts of skin growth factors and providing deep, rapid skin penetration.
Immune-Strengthening Ingredients
With more than 26 anti-inflammatory compounds, “sen” helps restore and protect skin compromised by reduced immunity,
promoting healthier, more resilient skin.
Medical-Grade Manufacturing Safety
“sen” meets Japan’s strict 120-day cosmetic raw material safety testing process and uses tissue cells cleared under national safety standards.
You can trust “sen” to be safe and effective for your skin.
The Excellence of “sen” Stem Cell Skincare
When stem cells are cultured, they secrete over 500 different skin-beautifying substances.
These powerful components are richly concentrated in the supernatant used in “sen.”
Key Ingredients in “sen”
Cytokines
Act as communication agents between skin cells, boosting natural repair power for trouble-free skin.
Exosomes
Deliver the “youth message” to skin cells, restoring firmness and glow from within.
Growth Factors (GFs)
Activate cells and support skin regeneration to fight aging signs.
EGF (Epidermal Growth Factor)
Promotes smooth and plump skin by regulating cell turnover.
FGF-1 / FGF-2 (Fibroblast Growth Factors)
Stimulate collagen production for firmer, elastic skin.
VEGF (Vascular Endothelial Growth Factor)
Enhances microcirculation for a brighter, more even complexion.
HGF (Hepatocyte Growth Factor)
Quickly repairs damaged skin to maintain healthy conditions.
KGF (Keratinocyte Growth Factor)
Strengthens skin barrier functions and protects against dryness and external irritants.
IGF-1 (Insulin-Like Growth Factor)
Boosts youthful elasticity and hydration, energizing the skin.
TGF-α (Transforming Growth Factor Alpha)
Normalizes cell turnover, resulting in luminous and clear skin.
PDGF (Platelet-Derived Growth Factor)
Promotes smoother skin texture and enhances regenerative power.
Experience Reborn Skin Like Never Before
Available in two concentration levels
TOPIX
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